Key Highlights
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Scientists have validated the first-ever questionnaire specifically designed for people with Functional Movement Disorders (FMD), a condition that causes involuntary movements without an underlying neurological disease. This new tool, called the FMD Questionnaire (FMDQ), allows doctors to accurately measure how the disorder affects a patient’s motor symptoms, daily activities, and social life, filling a critical gap that has hindered both patient care and research.
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A new study on Alzheimer’s drugs found that lecanemab, aducanumab, and donanemab all bind to similar types of amyloid beta protein clumps in the human brain, contradicting earlier ideas that lecanemab was more selective in its target. This finding challenges the theory that a drug’s specific binding preference is the main reason for lower rates of brain swelling (ARIAs) seen with lecanemab, suggesting other factors, such as a person’s APOE ε4 gene, play a more important role.
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Researchers have discovered that exposing pregnant mice to a ketogenic diet can help reduce aggressive behavior in their adult offspring that was caused by sleep deprivation late in pregnancy. This suggests that the mother’s diet might play a powerful role in protecting the developing brain from prenatal stress, potentially opening new avenues for understanding and preventing behavioral problems linked to poor sleep during pregnancy.
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