Key Highlights
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Among over 300,000 people aged 50+, annual mortality for those with both cancer and an expanded definition of heart failure (HFexp) ranged from 14.5% to 28.4%, with a similar proportion of deaths attributed to cancer and cardiovascular disease. This highlights the poor prognosis and dual burden in patients suffering from both conditions.
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A novel PREDICT-STEMI score, derived from 23,086 patients, uses seven variables (including age, diabetes, and haemodynamic status) to predict long-term mortality after PCI for ST-elevation myocardial infarction. Patients with a high score (≥60 points) had a sixfold increased risk of long-term mortality, offering clinicians a simple tool for early risk stratification.
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Mendelian randomisation analysis found limited genetic evidence directly linking chronic respiratory disease (CRD) and cardiovascular disease (CVD), though a nominally significant association was observed between asthma and an increased risk of atrial fibrillation. However, the study shows that smoking and inflammatory markers like IL6R and IL1RN commonly affect both CRD and CVD risk.
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Science Briefing
