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A new study found that combining two treatments—one that fixes the faulty SMN2 gene and another that blocks an enzyme called HDAC6—greatly improved muscle strength and survival in a mouse model of spinal muscular atrophy (SMA). This is important because it offers a potential way to help SMA patients who still face muscle weakness even after receiving newer gene therapies.

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Home - Medicine - Acute stress directly impairs the brain’s ability to learn from new experiences by altering neurochemical and genetic activity in the orbitofrontal cortex, the region responsible for decision-making. This finding highlights how everyday stressors can have a tangible, negative impact on cognitive flexibility and mental performance.

Medicine

Acute stress directly impairs the brain’s ability to learn from new experiences by altering neurochemical and genetic activity in the orbitofrontal cortex, the region responsible for decision-making. This finding highlights how everyday stressors can have a tangible, negative impact on cognitive flexibility and mental performance.

Last updated: May 4, 2026 9:26 am
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Acute stress directly impairs the brain’s ability to learn from new experiences by altering neurochemical and genetic activity in the orbitofrontal cortex, the region responsible for decision-making. This finding highlights how everyday stressors can have a tangible, negative impact on cognitive flexibility and mental performance.
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Cancer cells can become resistant to radiation therapy by entering a dormant-like state, driven by a specific protein modification (ubiquitination of DDX21 by HERC2) that activates a key cellular pathway. Understanding this mechanism opens the door to developing new treatments that could make cancer cells more vulnerable to radiation, improving outcomes for colorectal cancer patients.
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A new study shows that a faster, free-breathing MRI technique is just as effective as traditional respiratory-triggered methods for measuring liver chemistry, but cuts the scanning time by nearly three minutes. This advancement could make liver scans more comfortable and accessible for patients, without sacrificing diagnostic quality.
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Previous Article A comprehensive review of community-based studies across East and Southeast Asia reveals a critical lack of synthesized data on aging, highlighting the urgent need for more harmonized research to inform public health policies for the region’s rapidly growing older population. This finding underscores the importance of investing in large-scale, standardized longitudinal aging studies to effectively address the health challenges of an aging society.
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