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Home - Medicine - Unusual Coronary Flow: A Case of Apical Hypertrophic Cardiomyopathy

Medicine

Unusual Coronary Flow: A Case of Apical Hypertrophic Cardiomyopathy

Last updated: February 12, 2026 12:55 pm
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Unusual Coronary Flow: A Case of Apical Hypertrophic Cardiomyopathy

A case report details a woman in her 70s with a history of breast cancer who presented with exertional dyspnoea and chest pain. Diagnostic workup, including cardiac MRI, confirmed apical hypertrophic cardiomyopathy (HCM), characterized by systolic apical obliteration. Coronary angiography revealed a tortuous left anterior descending artery with prominent microvascular blush and drainage into the left ventricular cavity, while adenosine testing showed increased resting flow and an impaired hyperaemic response.

Why it might matter to you:
This case highlights a specific, complex presentation of chest pain that intersects cardiology and oncology, directly relevant to acute care evaluation. Understanding such atypical coronary physiology and its link to structural heart disease is crucial for accurate diagnosis and management in emergency and inpatient settings. It reinforces the importance of integrating advanced imaging and functional testing to guide evidence-based clinical decision-making for patients with overlapping cardiovascular symptoms.


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