Key Highlights
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A large phase 3 trial found only weak and inconsistent links between brain volume loss measured by MRI and actual disability worsening in people with primary progressive multiple sclerosis over two years. This questions whether commonly used MRI measures are suitable as a primary endpoint for clinical trials in this condition.
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New research reveals that nonnutritive sweeteners, commonly used in diet foods and drinks, may be involved in how the brain learns to prefer sugar, based on studies in rodents. This work helps clarify the complex relationship between sweet taste and the body’s energy needs, with potential implications for understanding human appetite.
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