Key Highlights
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A large analysis of over 500,000 older US adults found that getting two doses of the recombinant shingles vaccine (RZV) was linked to a 33% lower chance of developing new dementia and a 28% lower chance of developing Alzheimer’s disease over three years of follow-up.
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The protective effect was strongest for vascular dementia (a 33% lower risk), suggesting that the shingles vaccine may help protect the brain by reducing inflammation or affecting blood vessels, offering a potential new way to help prevent cognitive decline.
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A new simple scoring system, called PREDICT-STEMI, was developed from over 23,000 patients to accurately predict long-term death risk after a heart attack and stent procedure, achieving over 80% accuracy in multiple test groups.
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The score uses seven easily available factors (like age, diabetes history, and blood flow status) to place patients into risk groups, where those with a high score had a six times greater risk of death, which can help doctors make faster, more personalized treatment decisions.
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A study of over 500,000 people found that having a greater sense of psychological well-being (feeling happy, satisfied, and having purpose) was a strong predictor of living longer, even after accounting for negative mental health factors like depression and anxiety.
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This finding suggests that simply not being mentally ill is not enough; actively promoting positive mental health and life satisfaction could be an important, independent factor for improving public health and extending lifespan.
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