Charting the Proteome: A New Map for Precision Medicine
A new perspective article in the Journal of Molecular Biology argues that a comprehensive understanding of the human proteome is the next critical frontier for realizing the promise of precision medicine. The author, Fuchu He, posits that while genomics has provided a foundational blueprint, it is the dynamic and complex world of proteins—their structures, modifications, and interactions—that holds the key to truly personalized diagnostics and therapeutics. This navigation of the proteome is presented as an essential step to move from genetic predisposition to functional, mechanistic understanding of disease.
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