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A new study found that combining two treatments—one that fixes the faulty SMN2 gene and another that blocks an enzyme called HDAC6—greatly improved muscle strength and survival in a mouse model of spinal muscular atrophy (SMA). This is important because it offers a potential way to help SMA patients who still face muscle weakness even after receiving newer gene therapies.

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Home - Chemistry - Key Highlights in Medicinal Chemistry this Week

Chemistry

Key Highlights in Medicinal Chemistry this Week

Last updated: May 4, 2026 9:56 am
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A new study demonstrates that nanocomposites made of thermoplastic polyurethanes and gold nanoparticles exhibit a photoinduced shape memory effect. This breakthrough offers a potential route for developing responsive materials for biomedical applications, such as self-repairing implants or drug delivery systems.
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Researchers evaluated the dermal bioactivity of metal additive manufacturing powders using human in vitro and ex vivo skin models. This research is critical for assessing the safety of materials used in 3D printing, helping to identify potential skin irritation risks before these metals are used in medical implants or wearable devices.
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Takuzo Aida, a renowned chemist, reflects on his career researching the path to better polymers ahead of his 70th birthday. His work has significant implications for designing advanced materials with improved properties, which can be used in everything from plastics to medical devices.
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Previous Article Living closer to a facility that releases lead is linked to poorer memory. In a large study of older adults, those whose homes were 5 kilometers closer to a lead-releasing facility had a slightly lower score on episodic memory tests two years later, suggesting that environmental lead exposure may harm brain health even in older age.
Next Article A new study reveals that mitochondrial fission factor (MFF) is a key regulator of appetite-controlling AgRP neurons in the brain, where its deficiency increases calcium uptake and neuronal excitability to enhance food intake. This discovery highlights a specific molecular mechanism in the hypothalamus that could be targeted to better understand and manage metabolic disorders and body weight control.
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