Key Highlights
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A new case series provides evidence that Alzheimer’s disease pathology can be transmitted through certain medical procedures, a phenomenon known as iatrogenic Alzheimer’s disease. This finding is crucial as it suggests a potential new route of disease transmission and highlights the importance of safety protocols in medicine.
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In a mouse model of Alzheimer’s, only female mice showed early signs of the disease like sleep disruption and circadian rhythm problems, which were improved by a drug that reduces brain inflammation without clearing amyloid plaques. This points to neuroinflammation as a key, treatable cause of sleep problems in Alzheimer’s, especially in women.
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A study in adolescents with chronic pain found that the difficulty pain causes in daily life (pain interference) is what leads to increased pain medication use over time, not necessarily catastrophic thoughts about pain. This means treatments should focus on improving function and daily life, not just changing negative thoughts.
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