Key Highlights
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A new study found that poor sleep quality in early midlife is linked to higher levels of a brain protein called neurofilament light chain (NfL) 20 years later, which is a marker of nerve cell damage. This suggests that improving sleep habits earlier in life could be a way to help protect brain health and potentially reduce the risk of Alzheimer’s disease later on.
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Researchers have identified that the orphan receptor GPR84 plays a key role in driving the harmful inflammation seen in Buruli ulcer, a serious skin infection. This discovery points to GPR84 as a potential new target for developing treatments to stop the excessive inflammation that causes tissue damage in this disease.
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A clinical trial showed that adding the antibiotic tobramycin to vancomycin did not reduce deep surgical site infections in patients with high-risk tibial fractures compared to using vancomycin alone. This finding is important because it challenges the common practice of using multiple antibiotics for prevention, helping to avoid unnecessary antibiotic use and its associated risks.
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