Key Highlights
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A new computer model called DyCelFEM can now simulate the complex process of skin wound healing, including how cells move, change shape, and communicate with each other. This allows scientists to study and potentially improve healing in a virtual environment before testing treatments on real people.
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In metastatic melanoma, a protein called lamin B receptor is found at higher levels, and this makes the protective membrane around the cell’s nucleus more fragile when the cancer cell squeezes through tight spaces in the body. This nuclear damage during migration could be a new weak spot to target in order to stop cancer from spreading.
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A correction has been issued for a 2017 study on a protein called Smurf1, which was found to control the breakdown of another protein (Kindlin-2) that helps cells stick to their surroundings. This correction ensures the scientific record is accurate for future research into how cells manage this critical sticking process, which is important in both health and disease.
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