Key Highlights
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A new review reveals that cancer cells can switch between two distinct invasion styles—amoeboid and mesenchymal—to squeeze through tissue barriers, a process called invasion plasticity.
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The study explains how cells control this shape-shifting with protein-digesting enzymes (proteases), highlighting new potential targets to stop cancer from spreading.
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Computer-based “docking” simulations, a cornerstone of modern drug discovery, have become faster and smarter, allowing scientists to virtually screen millions of molecules to find promising drug candidates.
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This review highlights how these advanced screening methods can identify novel small molecules that act as molecular probes or starting points for new medicines, accelerating the journey from lab to clinic.
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