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Home - Neurology - The Sleep Connection: How Disturbed Rest May Accelerate Alzheimer’s Pathology

Neurology

The Sleep Connection: How Disturbed Rest May Accelerate Alzheimer’s Pathology

Last updated: April 2, 2026 1:10 pm
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The Sleep Connection: How Disturbed Rest May Accelerate Alzheimer’s Pathology

A longitudinal analysis of over 1,200 participants from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) provides new clinical evidence linking sleep disturbance to the progression of Alzheimer’s disease. The study found that baseline sleep disturbance was associated with a faster rate of decline in cerebrospinal fluid amyloid-beta 42 levels, a key biomarker of Alzheimer’s pathology.

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