The Immune System’s Fingerprint on Mania: A Proteomic Clue from Platelets
A new proof-of-concept study uses high-resolution platelet proteomics to investigate the biological underpinnings of mania in bipolar disorder. Researchers performed liquid chromatography–tandem mass spectrometry on platelets from hospitalized patients with severe mania and matched healthy controls, revealing a distinct proteomic signature.
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