The Gut’s Social Network: How Bacterial Interactions Rewire Metabolism
A new study in Nature Ecology & Evolution reveals the profound and complex ways human gut bacteria communicate and adapt to one another. Researchers analyzed the responses of 15 diverse bacterial species in over 100 pairwise co-cultures, uncovering extensive, species-specific remodelling of the bacterial proteome—the complete set of proteins an organism can produce. This reprogramming goes far beyond simple competition or cooperation, leading to emergent metabolic activities that are not present when the species are grown in isolation.
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