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Last updated: July 5, 2026 11:01 am
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Insulin Resistance Indices Predict Cardiovascular Risk in NAFLD and MASLD

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Discovery of the day  ·  Diabetes

Comparative performance of insulin resistance-related indices in predicting adverse cardiovascular events among individuals with NAFLD and MASLD: a multi-center cohort study

Dear Dr.Vijay Viswanathan, this is your personalized scientific intelligence briefing — curated for your work in Diabetes.

Key finding

Medicine · Diabetes

Discovery of the day

A multicenter cohort study directly compared the predictive performance of various insulin resistance-related indices for adverse cardiovascular events in patients with NAFLD and MASLD. Researchers found that certain indices demonstrated superior sensitivity in forecasting cardiovascular risk, providing a more refined tool for risk stratification in this high-risk population. For a clinician managing diabetes and its hepatic comorbidities in India, where NAFLD is highly prevalent, incorporating these validated indices into routine evaluation could substantially improve the early identification of patients requiring more intensive cardiovascular surveillance and intervention.

Novelty

75%

Rigor

85%

Significance

88%

Validity

82%

Clarity

90%


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