Key Highlights
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Integrating a genetic risk score and a blood-based transcriptional risk score significantly improved the early detection of Alzheimer’s disease across diverse populations, achieving a classification accuracy of 70.5% compared to 63.5% with genetic data alone. This combined approach offers a non-invasive, accessible alternative to costly or invasive biomarkers for screening.
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A new, large-scale study established the first age- and sex-specific normal values for heart strain rates in nearly 2,000 healthy adults. The research found that a lower-than-normal late diastolic strain rate (GSRa) was an independent predictor of major cardiovascular events, including heart failure and heart attack.
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An interim analysis of a randomized trial found that giving the maternal RSV vaccine during pregnancy, infant nirsevimab at birth, or a combination of both was safe and provided high antibody levels in infants through four months of follow-up. This research compares these prevention strategies for the first time in a single study.
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Science Briefing
