Key Highlights
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The effectiveness of an antibody’s ability to kill virus-infected cells (ADCC) depends primarily on which part of the virus it targets, not on how strongly it binds. This finding is crucial for designing better therapeutic antibodies and vaccines, as it shifts the focus from binding strength to target selection.
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Feeding fish a diet containing interferon produced by microalgae reshapes their gut microbiome to favor beneficial bacteria and reduces mortality from viral infections. This oral immunotherapy offers a promising, scalable strategy to protect aquaculture from devastating viral outbreaks.
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A breakdown in the cellular process that recycles introns—the non-coding parts of genes—leads to a buildup of double-stranded RNA inside cells, which can overwhelm the early warning system for viral infections. This discovery explains why cells with this defect are more susceptible to viruses and highlights a new link between basic gene processing and antiviral defense.
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Specialized immune cells called resident macrophages are essential for maintaining healthy pressure inside the eye by regulating the surrounding tissue structure. This finding reveals a previously unknown, non-inflammatory role for these immune cells and identifies a potential new target for treating glaucoma.
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