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Home - Medicine - Colonización bacteriana y progresión del cáncer gástrico: un vínculo inesperado of Medicine today

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Colonización bacteriana y progresión del cáncer gástrico: un vínculo inesperado of Medicine today

Last updated: March 31, 2026 11:03 am
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Colonización bacteriana y progresión del cáncer gástrico: un vínculo inesperado

Un estudio internacional, publicado en Cancer Discovery, ha identificado firmas mutacionales específicas y una mayor incidencia de hematopoyesis clonal (CH) en pacientes con metaplasia intestinal (MI), una condición premaligna del cáncer gástrico. La investigación, que analizó más de 1.500 muestras de MI de seis países, reveló que los pacientes con expansiones de CH presentaban un mayor riesgo de progresión a cáncer gástrico. Este hallazgo sugiere que las alteraciones somáticas no epiteliales pueden modular la inmunidad de la mucosa y el microambiente tumoral.

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