A New Target for Fibrosis: ROCK2 and the Liver’s Vascular Signals
A study in *Nature Reviews Drug Discovery* highlights ROCK2 as a promising, druggable target in liver fibrosis, focusing on its role in angiocrine signaling—the process by which blood vessels secrete factors that influence organ repair and disease. This research shifts the focus from general anti-fibrotic strategies to a specific molecular pathway that regulates the dysfunctional crosstalk between endothelial cells and the surrounding tissue.
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