Key Highlights
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A large study of pediatric coccidioidomycosis, a fungal infection, found that recurrence after treatment or simply watching without medication was rare, happening in only about 2% of cases. This suggests that for many children with this infection, careful monitoring without immediate drugs can be a safe option, potentially reducing unnecessary medication use.
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A new review highlights that Cushing syndrome, a disorder of high cortisol, is often missed because its symptoms are common, and current tests fail to capture the body’s natural daily cortisol rhythm. Measuring this daily pattern could lead to better diagnosis and treatment monitoring for this under-recognized condition.
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A major international guideline now recommends a procedure called renal denervation as an add-on treatment for patients with hard-to-control high blood pressure. This device-based therapy, which calms overactive nerves to the kidneys, offers a new option when medications alone aren’t enough to bring pressure down safely.
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A systematic review found that while advanced imaging techniques can help spot pre-cancerous changes in Barrett’s esophagus, they cannot yet safely replace the current standard method of taking many random biopsies. This means doctors should still use the traditional biopsy protocol to ensure nothing is missed during surveillance of this condition.
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A phase 3 trial showed that adding chemotherapy to a targeted drug (aumolertinib) significantly delayed cancer progression compared to the drug alone for patients with a specific type of lung cancer that also has other genetic mutations. This provides the first evidence that intensifying treatment based on a patient’s unique genetic profile can improve outcomes for this group.
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