Key Highlights
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The ketone body BHB, produced during a ketogenic diet, can reprogram CAR T cells—a type of cancer-fighting immune cell—to improve their energy, growth, and ability to attack tumors. This suggests that simple dietary supplements could be a practical way to boost the effectiveness of cutting-edge cancer immunotherapies.
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Researchers discovered a new antibody signature in patients with autoimmune hepatitis, linking the disease to reactivation of human herpesvirus 6 and to antibodies that block a receptor involved in reducing tissue scarring. This finding provides a clearer molecular link between a common virus and the development of a serious autoimmune liver disease.
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A study of trypanosome parasites, which cause diseases like sleeping sickness, reveals they repurposed an ancient cellular transport protein into a new, essential component for building their unique energy-producing organelles called glycosomes. This evolutionary repurposing highlights a potential new drug target for combating these neglected tropical diseases.
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Scientists developed a new statistical model that can accurately estimate animal population sizes even when animals move in and out of the study area, a common problem that previous methods failed to address. This advancement allows for more reliable wildlife monitoring and conservation planning, especially for mobile species like fish.
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An analysis of fish populations shows that marine heatwaves can boost fish numbers in the colder parts of their range while causing declines in warmer areas, revealing a complex “range-edge effect.” This finding is crucial for predicting how climate change will redistribute ocean life and impact global fisheries.
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