Key Highlights
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A large study found that older transfeminine adults, particularly those who have received gender-affirming hormone therapy, have higher odds of being diagnosed with Alzheimer’s disease and related dementias compared to cisgender men and women. This suggests dementia diagnosis and management should be a priority in the healthcare of this aging population.
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A new medical assistant-coached digital program (PRISM-CBT) that combines cognitive-behavioral therapy with resilience activities showed greater long-term reductions in pain interference and symptom burden for people with chronic spinal pain and fibromyalgia symptoms than standard CBT or usual care. This scalable program offers a promising new approach for managing widespread chronic pain.
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A study comparing subcutaneous immunoglobulin (SCIg) to intravenous immunoglobulin (IVIg) for neuroinflammatory diseases found that SCIg appears to have a lower risk of causing dangerous blood clots, especially for patients who already have other risk factors for heart disease or stroke. This makes SCIg a potentially safer long-term treatment option for many patients.
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A new review details how MRI can be used to create maps of tissue electrical conductivity, a property that changes with disease, offering a completely non-invasive way to gather more diagnostic information during a standard scan. This technology has the potential to improve the detection and monitoring of conditions like tumors or strokes without any extra procedures.
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A meta-analysis of 34 studies found that patients with severe aortic valve disease who also have advanced damage to the right side of their heart face a significantly higher risk of death and rehospitalization after a minimally invasive valve replacement procedure. This highlights the critical need to check for this type of heart damage before surgery to better plan patient care.
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