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Home - Medicine - A negative trial offers clarity on PCOS and pregnancy supplements

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A negative trial offers clarity on PCOS and pregnancy supplements

Last updated: January 23, 2026 1:13 am
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The latest discoveries in Endocrinology

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A negative trial offers clarity on PCOS and pregnancy supplements

A recent double-blind, placebo-controlled trial investigating the use of myo-inositol supplementation in pregnant individuals with polycystic ovary syndrome (PCOS) found no significant benefit in preventing pregnancy complications. This neutral finding contrasts with earlier, smaller studies that suggested a potential advantage. The result provides clinical reassurance that routine supplementation may not be necessary, helping to avoid unnecessary interventions and costs for patients.

Why it might matter to you:
This high-quality evidence directly informs clinical guidance for managing PCOS in pregnancy, a core aspect of gynecological endocrinology. It helps refine practice by identifying an intervention that may not warrant routine recommendation, allowing for a more streamlined and cost-effective approach to prenatal care. This supports a shift towards evidence-based stewardship of supplements in this patient population.


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