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Home - Rheumatology - A Head-to-Head Trial in Chronic Back Pain: Cooled vs. Standard Radiofrequency Ablation

Rheumatology

A Head-to-Head Trial in Chronic Back Pain: Cooled vs. Standard Radiofrequency Ablation

Last updated: March 15, 2026 5:25 am
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A Head-to-Head Trial in Chronic Back Pain: Cooled vs. Standard Radiofrequency Ablation

A recent multicenter, randomized clinical trial compared the effectiveness of two interventional pain management techniques for chronic facetogenic lumbar back pain: cooled radiofrequency ablation (CRFA) and standard radiofrequency ablation (SRFA). The study, published in *Regional Anesthesia & Pain Medicine*, involved patients who had confirmed facet joint pain via two positive medial branch blocks. The primary outcome was the proportion of patients achieving at least a 50% reduction in pain on the Numeric Rating Scale at six months. Results showed that both CRFA and SRFA provided robust, statistically significant, and clinically meaningful pain relief, with CRFA meeting the predefined non-inferiority criterion. Both treatments also led to significant improvements in disability, physical function, and quality-of-life metrics, which were sustained through a 12-month follow-up period.

Study Significance: For rheumatologists managing chronic musculoskeletal pain, this study provides high-level evidence supporting the efficacy of interventional procedures like radiofrequency ablation. The findings underscore that both cooled and standard techniques are viable options for providing durable pain relief and functional improvement in carefully selected patients with facetogenic low back pain, a common comorbidity in conditions like osteoarthritis and axial spondyloarthritis. This data can inform multidisciplinary treatment pathways and shared decision-making conversations with patients for whom pharmacologic therapies, including DMARDs and biologics, may not fully address structural pain sources.

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