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Home - Infectious Diseases - How Well Does the Flu Shot Protect Children? A Multi-Season Analysis

Infectious Diseases

How Well Does the Flu Shot Protect Children? A Multi-Season Analysis

Last updated: April 8, 2026 6:15 am
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How Well Does the Flu Shot Protect Children? A Multi-Season Analysis

A new study provides a robust, multi-year assessment of influenza vaccine effectiveness (VE) in children, a critical population where vaccination uptake remains suboptimal. Researchers analyzed data from over 19,000 children across seven US pediatric medical centers during the 2021–2024 influenza seasons. The study estimated VE against both influenza-associated hospitalizations and outpatient visits, revealing that overall effectiveness varied significantly by season, with the lowest protection observed in the 2021–2022 period.

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