Key Highlights
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A new deep learning tool called ALSNet can accurately identify different types of acute leukemia from microscope images of bone marrow, achieving high accuracy even when tested on images from different lab machines. This could help doctors diagnose this blood cancer faster and more reliably, especially in cases that are hard to classify by eye.
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In adolescents with chronic pain, the level of interference with daily life is a stronger predictor of future pain medication use than catastrophic thinking about pain. This finding suggests that helping young patients manage their pain-related disability may be more effective for reducing medication reliance than focusing only on their thoughts and fears.
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A targeted anti-inflammatory drug, MW151, improved sleep problems in female mice with Alzheimer’s-like brain changes without reducing the sticky amyloid plaques. This points to brain inflammation as a key, and quickly treatable, cause of sleep disruption in Alzheimer’s, which often affects women more.
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A large real-world study shows that the drug burosumab helps children with the rare bone disorder X-linked hypophosphatemia (XLH) grow taller at a faster rate. This treatment is predicted to lead to a greater final adult height for these patients.
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