The Sleep-Alzheimer’s Link: A Proteomic Pathway Emerges
A longitudinal study of over 1,200 participants from the Alzheimer’s Disease Neuroimaging Initiative provides robust clinical evidence linking sleep disturbance to the acceleration of Alzheimer’s pathology. The analysis found that baseline sleep problems were associated with a faster rate of decline in cerebrospinal fluid amyloid-beta (Aβ42) levels, a key biomarker of Alzheimer’s disease progression.
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