A New Lens on Ageing: The Endothelial Protein Fueling Cardiac Inflammation
A recent study has spotlighted a surprising player in cardiac ageing: non-glycanated decorin, a protein that accumulates in the ageing endothelium. This accumulation appears to trigger inflammatory pathways, potentially accelerating cardiovascular decline. While the findings open a novel mechanistic window into age-related heart disease, they also raise critical questions about the precise origins of this protein buildup and its specific role within the complex landscape of cardiac ageing.
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