Charting the Human Proteome: A New Map for Precision Medicine
A new perspective article in the Journal of Molecular Biology argues that a comprehensive understanding of the human proteome—the complete set of proteins expressed by our genome—is the next critical frontier for realizing the promise of precision medicine. While genomics has laid the essential groundwork, the author contends that proteins are the primary functional actors in health and disease, and their dynamic, tissue-specific expression holds the key to interpreting genetic variation.
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