Key Highlights
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A new study found that in a mouse model of Alzheimer’s, only female mice showed early signs of sleep disruption and unstable daily rhythms, which happened before memory problems appeared. This suggests that sleep and circadian issues may be an early, female-specific warning sign for Alzheimer’s, and that targeting brain inflammation could quickly improve sleep without needing to reduce brain plaques.
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A case series reports that Alzheimer’s disease pathology was found in patients who had received a specific medical treatment decades earlier, suggesting the disease can be transmitted between people under rare circumstances. This discovery is crucial as it confirms a previously suspected iatrogenic (treatment-caused) form of Alzheimer’s and highlights the importance of reviewing certain historical medical procedures for safety.
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A longitudinal study of teenagers with chronic pain found that the link between having catastrophic thoughts about pain and later using pain medication was explained by how much the pain interfered with daily life. This means that for young people with chronic pain, focusing on improving their ability to function day-to-day may be just as important as addressing their negative thoughts about pain when managing medication use.
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