Key Highlights
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Scientists have engineered special enzymes called ‘ene’-reductases to precisely create a specific chemical bond (an α,β-unsaturated carbonyl) in ring-shaped molecules. This breakthrough allows chemists to easily modify complex, ready-made molecules like terpenoids, opening new doors for creating potential drugs and other valuable chemicals.
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Researchers have developed a new method using a metal-organic framework (MOF) coating on a battery separator to actively scavenge water molecules. This innovation significantly improves the stability and lifespan of next-generation lithium metal batteries by preventing unwanted side reactions caused by moisture.
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A new spectroscopic technique can now separate the electric dipole and quadrupole signals from water molecules at surfaces and interfaces. This advancement provides a much clearer picture of how water behaves at the molecular level in critical environments like biological membranes or battery electrodes.
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The engineered enzyme platform can also produce chiral enones—molecules that are mirror images of each other—through a process called desaturative kinetic resolution. This is crucial for medicinal chemistry because the “handedness” of a molecule can determine its safety and effectiveness as a drug.
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