Key Highlights
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A study found that weight loss in Parkinson’s disease is linked to a distinct metabolic pattern, including reduced markers of sugar breakdown and increased markers of fat and protein breakdown. This suggests the body’s energy source shifts in Parkinson’s, highlighting potential metabolic targets for new treatments to prevent unhealthy weight loss.
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Researchers have successfully linked detailed clinical research data on Alzheimer’s disease with real-world electronic health records and Medicare claims for over 2,200 participants. This creates a much richer and more complete picture of a patient’s health journey, offering a powerful new model to accelerate personalized medicine for dementia.
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A study on eating behavior found that attention control in people who restrict their food intake can be influenced by sound and by non-invasive brain stimulation targeting the prefrontal cortex. This reveals how both external cues and specific brain circuits interact to affect attention in eating disorders, pointing to potential new therapy avenues.
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A case report highlights the challenge of distinguishing early signs of dementia with Lewy bodies from very-late-onset schizophrenia-like psychosis, even with brain imaging. This underscores the diagnostic complexity in older adults with new psychiatric symptoms, emphasizing the need for careful long-term evaluation.
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A clinical trial demonstrated that a specific brain stimulation technique, applied to both sides of the prefrontal cortex, was effective for treating depression in older adults. This provides a new, non-drug treatment option for late-life depression, which can be difficult to manage with medication alone.
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