Key Highlights
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A new case report details a rare fungal skin infection caused by Paraconiothyrium cyclothyrioides in a lung transplant patient in the United States. This highlights the risk of unusual fungal infections in immunocompromised individuals and the need for doctors to consider them in diagnosis.
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Global health organizations have announced that the supply of oral cholera vaccine is now sufficient to restart preventive vaccination campaigns for the first time in over three years. This is a major step forward in controlling cholera outbreaks, especially in vulnerable communities.
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A large study of over 5 million children found that mothers who took antibiotics during pregnancy had a 33% higher chance of their child developing an infection in childhood, with ear, nose, and throat infections being particularly common. This suggests doctors should be more cautious when prescribing antibiotics to pregnant women.
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A study in an area where a fungal disease called coccidioidomycosis is common found that most children with the infection recover well, and many did not even need antifungal medication. This research provides reassurance about the generally good outcomes for kids with this infection, even though doctors’ approaches to treatment vary widely.
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A phase 1 clinical trial shows that a reduced-dose regimen of the COVID-19 antiviral drug nirmatrelvir/ritonavir is safe and achieves effective drug levels in patients with severe kidney impairment, including those on dialysis. This provides a much-needed treatment option for a high-risk group that was previously excluded from using this effective medication.
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