Key Highlights
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A study in Kenya found that a smartphone game called Tumaini was effective at encouraging adolescents to delay their first sexual experience and to use condoms when they do become sexually active. This provides strong evidence that digital games can be a powerful and engaging tool for HIV prevention among young people in regions heavily affected by the virus.
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An economic evaluation from Canada shows that a simple program of mailing feedback to doctors about their antibiotic prescribing habits provides a positive return on investment for the public healthcare system. This means that a low-cost, non-punitive intervention can be a cost-effective way to combat the overuse of antibiotics, which is a major driver of antibiotic resistance.
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A phase 1 study found that a reduced dose of the COVID-19 antiviral Paxlovid (nirmatrelvir/ritonavir) is safe and maintains effective drug levels in patients with severe kidney impairment, including those on dialysis. This is crucial because these patients are at very high risk from COVID-19 but were previously excluded from standard treatment due to concerns about drug accumulation.
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A case report documents a rare fungal skin infection caused by *Paraconiothyrium cyclothyrioides* in a lung transplant patient in the United States. This highlights how patients with weakened immune systems, such as organ transplant recipients, are vulnerable to unusual and severe infections that require specialized diagnosis and treatment.
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A European study of patients with a lung disease linked to certain autoimmune antibodies found that nearly 40% of them also had kidney involvement. The research underscores that this condition is a multi-organ disease, requiring doctors to check kidney function and not just focus on the lungs.
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