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This week’s Medicine Key Highlights

Last updated: March 16, 2026 8:48 am
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Key Highlights

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A new study provides the first evidence that the COVID-19 antiviral Paxlovid (nirmatrelvir/ritonavir) is safe and maintains effective drug levels in patients with severe kidney disease, including those on dialysis. This is crucial because these patients are at very high risk from COVID-19, and doctors previously had to be very cautious with dosing due to concerns about drug buildup.
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A systematic review found that corticosteroid injections can provide short-term pain relief for children with certain musculoskeletal problems like hip pain, but the overall quality of evidence is very low. This highlights a significant gap, as there are no clear, evidence-based guidelines for using these common injections in kids, pointing to a need for larger, better studies.
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A major European study of over 1,600 patients reveals that lung disease linked to a specific type of autoimmune vasculitis is more common and severe than previously thought, with nearly half of patients dying within about 4 years. The findings stress that early detection and personalized treatment, potentially with drugs like rituximab, are critical for improving survival in this serious condition.
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Research shows that cardiac amyloidosis, a disease where abnormal proteins stiffen the heart, is not just a cause of heart failure with a strong heartbeat (preserved ejection fraction) but is found across the entire spectrum of heart weakness. Using a combination of heart imaging measurements provides a much better picture of a patient’s prognosis than any single test alone, guiding more personalized care.
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A clinical trial integrating simple, exposure-based talk therapy into intensive community mental health teams significantly reduced anxiety and improved quality of life for people with severe mental illnesses like schizophrenia. This demonstrates that structured psychological support is not only feasible in real-world community settings but can be a cost-effective way to address a major unmet need in this vulnerable population.
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