Obesity therapy shifts from risk factor to cardiovascular treatment target
A review in Heart synthesizes the rapidly evolving evidence that treating obesity itself should be considered a form of cardiovascular prevention. The authors argue that the era of merely advising weight loss is over, citing high-quality cardiovascular outcome trials for GLP-1 receptor agonists and bariatric surgery that demonstrate reductions in major cardiovascular events. This represents a paradigm shift, moving obesity from a contextual risk factor to a direct therapeutic target in cardiology.
Why it might matter to you:
The direct link between obesity management and improved hard cardiovascular outcomes has profound implications for managing patients with diabetes, where both conditions frequently coexist. This evidence strengthens the rationale for integrating newer anti-obesity pharmacotherapies into comprehensive care plans aimed at preventing macrovascular complications. It elevates the clinical conversation from general lifestyle advice to targeted, evidence-based intervention for a core driver of morbidity.
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