Bidirectional chemotherapy gets a second look for peritoneal spread
This “Author Reflections” piece in Annals of Surgical Oncology highlights the emerging rationale for bidirectional chemotherapy approaches in peritoneal carcinomatosis—strategies designed to intensify drug exposure both within the peritoneal cavity and systemically. While the article is not presented here with full methodological detail, the central takeaway is a clinical re-framing: for select patients with peritoneal disease, combining regional and systemic delivery may help address the pharmacologic limitations of either route alone and could influence how multidisciplinary teams think about sequencing with surgery and other locoregional therapies.
Why it might matter to you:
If you work with or interpret evidence in peritoneal metastasis, this reframes an active area where regimen design and delivery route can be as important as the drug itself. It can also help you track which patient-selection questions and endpoints (disease control in the peritoneum, toxicity trade-offs, integration with cytoreduction) are likely to drive the next wave of trials.
Melanoma diagnostics: a small correction with outsized importance
This notice corrects the article “Advances in the noninvasive diagnosis of melanoma—40 years beyond the ABCDs” in CA: A Cancer Journal for Clinicians. Although the correction text is not included in the feed content beyond the bibliographic pointer, the key point for readers is practical: any updated figures, wording, or data elements in a high-visibility clinician resource may affect how noninvasive melanoma assessment methods are interpreted, taught, or cited—especially in fast-moving areas such as dermoscopy, imaging, and AI-supported evaluation.
Why it might matter to you:
If you rely on review articles to guide diagnostic strategy or to support clinical pathways, corrections can change the precision of what you communicate to colleagues and trainees. It is also a reminder to update slide decks and reference lists so downstream decisions are based on the most accurate version.
Cancer care’s quiet engine: who sits on the board still matters
Annals of Oncology publishes its Editorial Board listing for the upcoming cycle. While not a research study, this is a signal document for the field: editorial leadership influences what kinds of oncology evidence are prioritized (trial design standards, endpoints, translational relevance, real-world data expectations), which topics receive commissioned reviews, and how rigor is enforced in peer review. For readers who publish, it also helps map the journal’s current areas of expertise and likely methodological expectations.
Why it might matter to you:
If you publish or track oncology evidence, shifts in editorial leadership can foreshadow changes in acceptance priorities and review strictness around statistics, biomarkers, and clinical meaningfulness. It can also help you identify emerging sub-areas the journal may be gearing up to feature more prominently.
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